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Calmodulin-dependent gating of Ca(v)1.2 calcium channels in the absence of Ca(v)β subunits
It is generally accepted that to generate calcium currents in response to depolarization, Ca(v)1.2 calcium channels require association of the pore-forming α(1C) subunit with accessory Ca(v)β and α(2)δ subunits. A single calmodulin (CaM) molecule is tethered to the C-terminal α(1C)-LA/IQ region and...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2430375/ https://ncbi.nlm.nih.gov/pubmed/18535142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711624105 |
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