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Functional properties of the Ca(v)1.2 calcium channel activated by calmodulin in the absence of α(2)δ subunits

Voltage-activated Ca(v)1.2 calcium channels require association of the pore-forming α(1C) subunit with accessory Ca(v)β and α(2)δ subunits. Binding of a single calmodulin (CaM) to α(1C) supports Ca(2+)-dependent inactivation (CDI). The human Ca(v)1.2 channel is silent in the absence of Ca(v)β and/or...

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Detalhes bibliográficos
Main Authors: Ravindran, Arippa, Kobrinsky, Evgeny, Lao, Qi Zong, Soldatov, Nikolai M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772127/
https://ncbi.nlm.nih.gov/pubmed/19106618
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