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Calmodulin-dependent gating of Ca(v)1.2 calcium channels in the absence of Ca(v)β subunits

It is generally accepted that to generate calcium currents in response to depolarization, Ca(v)1.2 calcium channels require association of the pore-forming α(1C) subunit with accessory Ca(v)β and α(2)δ subunits. A single calmodulin (CaM) molecule is tethered to the C-terminal α(1C)-LA/IQ region and...

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Detalhes bibliográficos
Main Authors: Ravindran, Arippa, Lao, Qi Zong, Harry, Jo Beth, Abrahimi, Parwiz, Kobrinsky, Evgeny, Soldatov, Nikolai M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430375/
https://ncbi.nlm.nih.gov/pubmed/18535142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711624105
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