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New Determinant for the Ca(V)β(2) Subunit Modulation of the Ca(V)1.2 Calcium Channel

Ca(v)β subunits support voltage gating of Ca(v)1.2 calcium channels and play important role in excitation-contraction coupling. The common central membrane-associated guanylate kinase (MAGUK) region of Ca(v)β binds to the α-interaction domain (AID) and the IQ motif of the pore-forming α(1C) subunit,...

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Autores principales: Lao, Qi Zong, Kobrinsky, Evgeny, Harry, Jo Beth, Ravindran, Arippa, Soldatov, Nikolai M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2414265/
https://ncbi.nlm.nih.gov/pubmed/18411278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802035200
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