Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors

Recognition of microbial components by germ-line encoded pattern recognition receptors (PRR) initiates immune responses to infectious agents. We and others have proposed that pairs or sets of PRR mediate host immunity. One such pair comprises the fungal β-glucan receptor, Dectin-1, which collaborate...

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Bibliographic Details
Main Authors: Dennehy, Kevin M, Ferwerda, Gerben, Faro-Trindade, Inês, Pyż, Elwira, Willment, Janet A, Taylor, Philip R, Kerrigan, Ann, Tsoni, S Vicky, Gordon, Siamon, Meyer-Wentrup, Friederike, Adema, Gosse J, Kullberg, Bart-Jan, Schweighoffer, Edina, Tybulewicz, Victor, Mora-Montes, Hector M, Gow, Neil A R, Williams, David L, Netea, Mihai G, Brown, Gordon D
Format: Artigo
Language:Inglês
Published: WILEY-VCH Verlag 2008
Subjects:
Innate immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430329/
https://ncbi.nlm.nih.gov/pubmed/18200499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200737741
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