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Dectin-1 is required for β-glucan recognition and control of fungal infection

β-Glucan is one of the most abundant polysaccharides in fungal pathogens, yet its importance in antifungal immunity is unclear. Here we show that deficiency of dectin-1, the myeloid receptor for β-glucan, rendered mice susceptible to infection with Candida albicans. Dectin-1-deficient leukocytes dem...

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Detalhes bibliográficos
Main Authors: Taylor, Philip R, Tsoni, S Vicky, Willment, Janet A, Dennehy, Kevin M, Rosas, Marcela, Findon, Helen, Haynes, Ken, Steele, Chad, Botto, Marina, Gordon, Siamon, Brown, Gordon D
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1888731/
https://ncbi.nlm.nih.gov/pubmed/17159984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1408
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