Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection

Innate immune cells detect pathogens via pattern recognition receptors (PRRs), which signal for initiation of immune responses to infection. Studies with Dectin-1, a PRR for fungi, have defined a novel innate signaling pathway involving Syk kinase and the adaptor CARD9, which is critical for inducin...

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Detalhes bibliográficos
Main Authors: Robinson, Matthew J., Osorio, Fabiola, Rosas, Marcela, Freitas, Rui P., Schweighoffer, Edina, Groß, Olaf, Verbeek, J. Sjef, Ruland, Jürgen, Tybulewicz, Victor, Brown, Gordon D., Moita, Luis Ferreira, Taylor, Philip R., Reis e Sousa, Caetano
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737172/
https://ncbi.nlm.nih.gov/pubmed/19703985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20082818
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