HIV-1 Tat protein alter the tight junction integrity and function of retinal pigment epithelium: an in vitro study

BACKGROUND: How HIV-1 enter into the eyes remains obscure. We postulated that HIV-1 Tat protein can alter the expression of specific tight-junction proteins and disturb the blood retinal barrier, and contributes to HIV trafficking into the eyes. This study is to determine the effects of HIV-1 Tat pr...

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Main Authors: Bai, Ling, Zhang, Zhenping, Zhang, Hui, Li, Xiumei, Yu, Qiurong, Lin, Haotian, Yang, Wenhui
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430207/
https://ncbi.nlm.nih.gov/pubmed/18538010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-8-77
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