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Effects of Proinflammatory Cytokines on the Claudin-19 Rich Tight Junctions of Human Retinal Pigment Epithelium

PURPOSE. Chronic, subclinical inflammation contributes to the pathogenesis of several ocular diseases, including age-related macular degeneration. Proinflammatory cytokines affect tight junctions in epithelia that lack claudin-19, but in the retinal pigment epithelium claudin-19 predominates. We exa...

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Detalhes bibliográficos
Main Authors: Peng, Shaomin, Gan, Geliang, Rao, Veena S., Adelman, Ron A., Rizzolo, Lawrence J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410691/
https://ncbi.nlm.nih.gov/pubmed/22761260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8311
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