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Knockdown of Claudin-19 in the Retinal Pigment Epithelium Is Accompanied by Slowed Phagocytosis and Increased Expression of SQSTM1

PURPOSE: Besides regulating paracellular diffusion, claudin-19 modulates the expression of proteins essential for the retinal pigment epithelium (RPE). This study asks how RPE responds when the expression of claudin-19 is reduced. METHODS: In stem cell-derived RPE, claudin-19 and sequestosome-1/p62...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Liu, Fanfei, Peng, Shaomin, Adelman, Ron A., Rizzolo, Lawrence J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7900869/
https://ncbi.nlm.nih.gov/pubmed/33591357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.62.2.14
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