RAGE mediated intracellular Aβ uptake contributes to the breakdown of tight junction in retinal pigment epithelium

Intracellular amyloid beta (Aβ) has been implicated in neuronal cell death in Alzheimer's disease (AD). Intracellular Aβ also contributes to tight junction breakdown of retinal pigment epithelium (RPE) in age-related macular degeneration (AMD). Although Aβ is predominantly secreted from neurona...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Park, Sung Wook, Kim, Jin Hyoung, Park, Sang Min, Moon, Minho, Lee, Kihwang, Park, Kyu Hyung, Park, Woo Jin, Kim, Jeong Hun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper: Gerotarget (Focus on Aging)
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742103/
https://ncbi.nlm.nih.gov/pubmed/26431165
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