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Tight junction composition is altered in the epithelium of polycystic kidneys
Kidney cysts in autosomal dominant polycystic kidney disease (ADPKD) undergo progressive enlargement together with luminal fluid secretion. This involves active, uphill transcellular Cl(−) transport which drives passive Na(+) and water secretion. Implicit in this mechanism is the assumption that the...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2614395/ https://ncbi.nlm.nih.gov/pubmed/18666097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2392 |
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