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Endotoxemia alters tight junction gene and protein expression in the kidney

Intact tight junctional (TJ) proteins are required for tubular ion transport and waste excretion. Disruption of TJs may contribute to a decreased glomerular filtration rate in acute kidney injury (AKI) via tubular backleak. The effect of LPS-mediated AKI on murine TJs has not been studied extensivel...

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Detalhes bibliográficos
Main Authors: Eadon, Michael T., Hack, Bradley K., Xu, Chang, Ko, Benjamin, Toback, F. Gary, Cunningham, Patrick N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468522/
https://ncbi.nlm.nih.gov/pubmed/22791339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00023.2012
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