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TNF-mediated damage to glomerular endothelium is an important determinant of acute kidney injury in sepsis

Severe sepsis is often accompanied by acute kidney injury (AKI) and albuminuria. Here we studied whether the AKI and albuminuria associated with lipopolysaccharide (LPS) treatment in mice reflects impairment of the glomerular endothelium with its associated endothelial surface layer. LPS treatment d...

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Detalhes bibliográficos
Main Authors: Xu, Chang, Chang, Anthony, Hack, Bradley K., Eadon, Michael T., Alper, Seth L., Cunningham, Patrick N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834073/
https://ncbi.nlm.nih.gov/pubmed/23903370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2013.286
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