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TNF-mediated damage to glomerular endothelium is an important determinant of acute kidney injury in sepsis

Severe sepsis is often accompanied by acute kidney injury (AKI) and albuminuria. Here we studied whether the AKI and albuminuria associated with lipopolysaccharide (LPS) treatment in mice reflects impairment of the glomerular endothelium with its associated endothelial surface layer. LPS treatment d...

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Détails bibliographiques
Auteurs principaux: Xu, Chang, Chang, Anthony, Hack, Bradley K., Eadon, Michael T., Alper, Seth L., Cunningham, Patrick N.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834073/
https://ncbi.nlm.nih.gov/pubmed/23903370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2013.286
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