Generation of a genomic tiling array of the human Major Histocompatibility Complex (MHC) and its application for DNA methylation analysis

BACKGROUND: The major histocompatibility complex (MHC) is essential for human immunity and is highly associated with common diseases, including cancer. While the genetics of the MHC has been studied intensively for many decades, very little is known about the epigenetics of this most polymorphic and...

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Main Authors: Tomazou, Eleni M, Rakyan, Vardhman K, Lefebvre, Gregory, Andrews, Robert, Ellis, Peter, Jackson, David K, Langford, Cordelia, Francis, Matthew D, Bäckdahl, Liselotte, Miretti, Marcos, Coggill, Penny, Ottaviani, Diego, Sheer, Denise, Murrell, Adele, Beck, Stephan
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2008
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430202/
https://ncbi.nlm.nih.gov/pubmed/18513384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-1-19
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