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Reconfiguration of genomic anchors upon transcriptional activation of the human major histocompatibility complex

The folding of chromatin into topologically constrained loop domains is essential for genomic function. We have identified genomic anchors that define the organization of chromatin loop domains across the human major histocompatibility complex (MHC). This locus contains critical genes for immunity a...

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Hlavní autoři: Ottaviani, Diego, Lever, Elliott, Mitter, Richard, Jones, Tania, Forshew, Tim, Christova, Rossitza, Tomazou, Eleni M., Rakyan, Vardhman K., Krawetz, Stephen A., Platts, Adrian E., Segarane, Badmavady, Beck, Stephan, Sheer, Denise
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577859/
https://ncbi.nlm.nih.gov/pubmed/18849521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.082313.108
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