Generation of a genomic tiling array of the human Major Histocompatibility Complex (MHC) and its application for DNA methylation analysis

BACKGROUND: The major histocompatibility complex (MHC) is essential for human immunity and is highly associated with common diseases, including cancer. While the genetics of the MHC has been studied intensively for many decades, very little is known about the epigenetics of this most polymorphic and...

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Detalhes bibliográficos
Main Authors: Tomazou, Eleni M, Rakyan, Vardhman K, Lefebvre, Gregory, Andrews, Robert, Ellis, Peter, Jackson, David K, Langford, Cordelia, Francis, Matthew D, Bäckdahl, Liselotte, Miretti, Marcos, Coggill, Penny, Ottaviani, Diego, Sheer, Denise, Murrell, Adele, Beck, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430202/
https://ncbi.nlm.nih.gov/pubmed/18513384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-1-19
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