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The conserved histidine 295 does not contribute to proton cotransport by the glutamate transporter EAAC1

Transmembrane glutamate transport by the excitatory amino acid carrier (EAAC1) is coupled to the cotransport of three Na(+) ions and one proton. Previously, we suggested that the mechanism of H(+) cotransport involves protonation of the conserved glutamate residue E373. However, it was also speculat...

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Autors principals: Tao, Zhen, Grewer, Christof
Format: Artigo
Idioma:Inglês
Publicat: 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430086/
https://ncbi.nlm.nih.gov/pubmed/15736956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi047812i
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