Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease

Osteosarcoma is the most common primary malignant tumor of bone. Analysis of familial cancer syndromes and sporadic cases has strongly implicated both p53 and pRb in its pathogenesis; however, the relative contribution of these mutations to the initiation of osteosarcoma is unclear. We describe here...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Walkley, Carl R., Qudsi, Rameez, Sankaran, Vijay G., Perry, Jennifer A., Gostissa, Monica, Roth, Sanford I., Rodda, Stephen J., Snay, Erin, Dunning, Patricia, Fahey, Frederic H., Alt, Frederick W., McMahon, Andrew P., Orkin, Stuart H.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Cold Spring Harbor Laboratory Press 2008
Θέματα:
Research Paper
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2428063/
https://ncbi.nlm.nih.gov/pubmed/18559481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1656808
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!

Παρόμοια τεκμήρια