تحميل...
Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease
Osteosarcoma is the most common primary malignant tumor of bone. Analysis of familial cancer syndromes and sporadic cases has strongly implicated both p53 and pRb in its pathogenesis; however, the relative contribution of these mutations to the initiation of osteosarcoma is unclear. We describe here...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , , , , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Cold Spring Harbor Laboratory Press
2008
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2428063/ https://ncbi.nlm.nih.gov/pubmed/18559481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1656808 |
| الوسوم: |
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