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Load and P(i) Control Flux through the Branched Kinetic Cycle of Myosin V
Myosin V is a processive actin-based motor protein that takes multiple 36-nm steps to deliver intracellular cargo to its destination. In the laser trap, applied load slows myosin V heavy meromyosin stepping and increases the probability of backsteps. In the presence of 40 mm phosphate (P(i)), both f...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2427344/ https://ncbi.nlm.nih.gov/pubmed/18441369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800539200 |
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