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A Branched Kinetic Scheme Describes the Mechanochemical Coupling of Myosin Va Processivity in Response to Substrate

Myosin Va is a double-headed cargo-carrying molecular motor that moves processively along cellular actin filaments. Long processive runs are achieved through mechanical coordination between the two heads of myosin Va, which keeps their ATPase cycles out of phase, preventing both heads detaching from...

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Detalhes bibliográficos
Main Authors: Zhang, Chong, Yusuf Ali, M., Warshaw, David M., Kad, Neil M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443780/
https://ncbi.nlm.nih.gov/pubmed/22947934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.07.033
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