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A Branched Kinetic Scheme Describes the Mechanochemical Coupling of Myosin Va Processivity in Response to Substrate

Myosin Va is a double-headed cargo-carrying molecular motor that moves processively along cellular actin filaments. Long processive runs are achieved through mechanical coordination between the two heads of myosin Va, which keeps their ATPase cycles out of phase, preventing both heads detaching from...

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Библиографические подробности
Главные авторы: Zhang, Chong, Yusuf Ali, M., Warshaw, David M., Kad, Neil M.
Формат: Artigo
Язык:Inglês
Опубликовано: The Biophysical Society 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443780/
https://ncbi.nlm.nih.gov/pubmed/22947934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.07.033
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