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The Role of the 14–20 Domain of the Islet Amyloid Polypeptide in Amyloid Formation

The molecular mechanism of amyloid formation by the islet amyloid polypeptide (IAPP) has been intensively studied since its identification in the late 1980s. The IAPP(20–29) region is considered to be the central amyloidogenic module of the polypeptide. This assumption is mainly based on the amyloid...

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Detalhes bibliográficos
Main Authors: Gilead, Sharon, Gazit, Ehud
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2426739/
https://ncbi.nlm.nih.gov/pubmed/18566678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2008/256954
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