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The Downstream Transcriptional Enhancer, Ed, Positively Regulates Mouse Igκ Gene Expression and Somatic Hypermutation
The mouse Igκ locus has three known transcriptional enhancers: the MAR/intronic enhancer (MEi), the 3′ enhancer (E3′) and the further downstream enhancer (Ed). Previous studies have shown that both MEi and E3′ enhancers are required for maximal gene rearrangement of the locus, and that E3′ is also r...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2424255/ https://ncbi.nlm.nih.gov/pubmed/18453592 |
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