Discovery of agents that eradicate leukemia stem cells using an in silico screen of public gene expression data

Increasing evidence indicates that malignant stem cells are important for the pathogenesis of acute myelogenous leukemia (AML) and represent a reservoir of cells that drive the development of AML and relapse. Therefore, new treatment regimens are necessary to prevent relapse and improve therapeutic...

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Bibliographic Details
Main Authors: Hassane, Duane C., Guzman, Monica L., Corbett, Cheryl, Li, Xiaojie, Abboud, Ramzi, Young, Fay, Liesveld, Jane L., Carroll, Martin, Jordan, Craig T.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2008
Subjects:
Neoplasia
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2424160/
https://ncbi.nlm.nih.gov/pubmed/18305216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-11-126003
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