Rapid and selective death of leukemia stem and progenitor cells induced by the compound 4-benzyl, 2-methyl, 1,2,4-thiadiazolidine, 3,5 dione (TDZD-8)

Leukemia is thought to arise from malignant stem cells, which have been described for acute and chronic myeloid leukemia (AML and CML) and for acute lymphoblastic leukemia (ALL). Leukemia stem cells (LSCs) are relatively resistant to current chemotherapy and likely contribute to disease relapse and...

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Hlavní autoři: Guzman, Monica L., Li, Xiaojie, Corbett, Cheryl A., Rossi, Randall M., Bushnell, Timothy, Liesveld, Jane L., Hébert, Josée, Young, Fay, Jordan, Craig T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2007
Témata:
Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234782/
https://ncbi.nlm.nih.gov/pubmed/17785584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-088815
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