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Novel mTOR inhibitory activity of ciclopirox enhances parthenolide antileukemia activity
Ciclopirox, an antifungal agent commonly used for the dermatologic treatment of mycoses, has been shown recently to have antitumor properties. Although the exact mechanism of ciclopirox is unclear, its antitumor activity has been attributed to iron chelation and inhibition of the translation initiat...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3809917/ https://ncbi.nlm.nih.gov/pubmed/23660068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2013.04.012 |
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