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Novel mTOR inhibitory activity of ciclopirox enhances parthenolide antileukemia activity

Ciclopirox, an antifungal agent commonly used for the dermatologic treatment of mycoses, has been shown recently to have antitumor properties. Although the exact mechanism of ciclopirox is unclear, its antitumor activity has been attributed to iron chelation and inhibition of the translation initiat...

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Bibliografische gegevens
Hoofdauteurs: Sen, Siddhartha, Hassane, Duane C., Corbett, Cheryl, Becker, Michael W., Jordan, Craig T., Guzman, Monica L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809917/
https://ncbi.nlm.nih.gov/pubmed/23660068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2013.04.012
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