טוען...

Degradation of fibrillar forms of Alzheimer’s amyloid β-peptide by macrophages

Cultured microglia internalize fibrillar amyloid Aβ (fAβ) and deliver it to lysosomes. Degradation of fAβ by microglia is incomplete, but macrophages degrade fAβ efficiently. When mannose-6 phosphorylated lysosomal enzymes were added to the culture medium of microglia, degradation of fAβ was increas...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Majumdar, Amitabha, Chung, Haeyong, Dolios, Georgia, Wang, Rong, Asamoah, Nikiya, Lobel, Peter, Maxfield, Frederick R.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2424018/
https://ncbi.nlm.nih.gov/pubmed/17222479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2006.12.001
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