A carregar...
ATR Kinase Activation Mediated by MutSα and MutLα in Response to Cytotoxic O(6)-Methylguanine Adducts
S(N)1-type alkylating agents that produce cytotoxic O(6)-methyl-G (O(6)-meG) DNA adducts induce cell cycle arrest and apoptosis in a manner requiring the DNA mismatch repair (MMR) proteins MutSα and MutLα. Here, we show that checkpoint signaling in response to DNA methylation occurs during S phase a...
Na minha lista:
| Main Authors: | , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2423943/ https://ncbi.nlm.nih.gov/pubmed/16713580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.04.023 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|