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Abl N-terminal Cap stabilization of SH3 domain dynamics
Crystal structures and other biochemical data indicate that the N-terminal cap (NCap) region of the Abelson tyrosine kinase (c-Abl) is important for maintaining the downregulated conformation of the kinase domain. The exact contributions that NCap makes in stabilizing the various intramolecular inte...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2423811/ https://ncbi.nlm.nih.gov/pubmed/18452309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800446b |
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