DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice

Chronic inflammation increases cancer risk. While it is clear that cell signaling elicited by inflammatory cytokines promotes tumor development, the impact of DNA damage production resulting from inflammation-associated reactive oxygen and nitrogen species (RONS) on tumor development has not been di...

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Main Authors: Meira, Lisiane B., Bugni, James M., Green, Stephanie L., Lee, Chung-Wei, Pang, Bo, Borenshtein, Diana, Rickman, Barry H., Rogers, Arlin B., Moroski-Erkul, Catherine A., McFaline, Jose L., Schauer, David B., Dedon, Peter C., Fox, James G., Samson, Leona D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423313/
https://ncbi.nlm.nih.gov/pubmed/18521188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35073
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