DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice

Chronic inflammation increases cancer risk. While it is clear that cell signaling elicited by inflammatory cytokines promotes tumor development, the impact of DNA damage production resulting from inflammation-associated reactive oxygen and nitrogen species (RONS) on tumor development has not been di...

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Main Authors: Meira, Lisiane B., Bugni, James M., Green, Stephanie L., Lee, Chung-Wei, Pang, Bo, Borenshtein, Diana, Rickman, Barry H., Rogers, Arlin B., Moroski-Erkul, Catherine A., McFaline, Jose L., Schauer, David B., Dedon, Peter C., Fox, James G., Samson, Leona D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2008
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423313/
https://ncbi.nlm.nih.gov/pubmed/18521188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35073
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