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Silencing of (A)γ-Globin Gene Expression during Adult Definitive Erythropoiesis Mediated by GATA-1-FOG-1-Mi2 Complex Binding at the −566 GATA Site
Autonomous silencing of γ-globin transcription is an important developmental regulatory mechanism controlling globin gene switching. An adult stage-specific silencer of the (A)γ-globin gene was identified between −730 and −378 relative to the mRNA start site. A marked copy of the (A)γ-globin gene in...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2423176/ https://ncbi.nlm.nih.gov/pubmed/18347053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01858-07 |
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