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Silencing of (A)γ-Globin Gene Expression during Adult Definitive Erythropoiesis Mediated by GATA-1-FOG-1-Mi2 Complex Binding at the −566 GATA Site

Autonomous silencing of γ-globin transcription is an important developmental regulatory mechanism controlling globin gene switching. An adult stage-specific silencer of the (A)γ-globin gene was identified between −730 and −378 relative to the mRNA start site. A marked copy of the (A)γ-globin gene in...

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Detalhes bibliográficos
Main Authors: Harju-Baker, Susanna, Costa, Flávia C., Fedosyuk, Halyna, Neades, Renee, Peterson, Kenneth R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423176/
https://ncbi.nlm.nih.gov/pubmed/18347053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01858-07
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