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ETO, but Not Leukemogenic Fusion Protein AML1/ETO, Augments RBP-Jκ/SHARP-Mediated Repression of Notch Target Genes

Notch is a transmembrane receptor that determines cell fates and pattern formation in all animal species. After specific ligand binding, the intracellular part of Notch is cleaved off and translocates to the nucleus, where it targets the DNA binding protein RBP-Jκ. In the absence of Notch, RBP-Jκ re...

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Bibliografski detalji
Glavni autori: Salat, Daniela, Liefke, Robert, Wiedenmann, Jörg, Borggrefe, Tilman, Oswald, Franz
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423149/
https://ncbi.nlm.nih.gov/pubmed/18332109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01966-07
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