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The TSC1-TSC2 Complex Is Required for Proper Activation of mTOR Complex 2
The mammalian target of rapamycin (mTOR) is a protein kinase that forms two functionally distinct complexes important for nutrient and growth factor signaling. Both complexes phosphorylate a hydrophobic motif on downstream protein kinases, which contributes to the activation of these kinases. mTOR c...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2423120/ https://ncbi.nlm.nih.gov/pubmed/18411301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00289-08 |
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