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Characterization of Rictor Phosphorylation Sites Reveals Direct Regulation of mTOR Complex 2 by S6K1

The mammalian target of rapamycin (mTOR) functions within two distinct complexes (mTORC1 and mTORC2) to control cell growth, proliferation, survival, and metabolism. While there has been great progress in our understanding of mTORC1 regulation, the signaling mechanisms that regulate mTORC2 have not...

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Autors principals: Dibble, Christian C., Asara, John M., Manning, Brendan D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772744/
https://ncbi.nlm.nih.gov/pubmed/19720745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00735-09
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