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The TSC1–TSC2 complex: a molecular switchboard controlling cell growth
TSC1 and TSC2 are the tumour-suppressor genes mutated in the tumour syndrome TSC (tuberous sclerosis complex). Their gene products form a complex that has become the focus of many signal transduction researchers. The TSC1–TSC2 (hamartin–tuberin) complex, through its GAP (GTPase-activating protein) a...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2735030/ https://ncbi.nlm.nih.gov/pubmed/18466115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20080281 |
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