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PTEN Represses RNA Polymerase III-Dependent Transcription by Targeting the TFIIIB Complex
PTEN, a tumor suppressor whose function is frequently lost in human cancers, possesses a lipid phosphatase activity that represses phosphatidylinositol 3-kinase (PI3K) signaling, controlling cell growth, proliferation, and survival. The potential for PTEN to regulate the synthesis of RNA polymerase...
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| Asıl Yazarlar: | , , , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology (ASM)
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2423115/ https://ncbi.nlm.nih.gov/pubmed/18391023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01912-07 |
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