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PTEN Represses RNA Polymerase I Transcription by Disrupting the SL1 Complex
PTEN is a tumor suppressor whose function is frequently lost in human cancer. It possesses a lipid phosphatase activity that represses the activation of PI3 kinase/Akt signaling, leading to decreased cell growth, proliferation, and survival. The potential for PTEN to regulate transcription of the la...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1190253/ https://ncbi.nlm.nih.gov/pubmed/16055704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.16.6899-6911.2005 |
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