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Distinct Roles for MyD88 and Toll-Like Receptors 2, 5, and 9 in Phagocytosis of Borrelia burgdorferi and Cytokine Induction
The contribution of Toll-like receptors (TLRs) to phagocytosis of Borrelia burgdorferi has not been extensively studied. We show that bone marrow-derived macrophages (BMDM) from MyD88(−/−) mice or Raw cells transfected with a dominant-negative MyD88 were unable to efficiently internalize B. burgdorf...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2423091/ https://ncbi.nlm.nih.gov/pubmed/18378636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01600-07 |
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