MyD88 Deficiency Results in Tissue-Specific Changes in Cytokine Induction and Inflammation in Interleukin-18-Independent Mice Infected with Borrelia burgdorferi

Toll-like receptors (TLRs) play an important role in the control of infection with Borrelia burgdorferi. Deficiencies in TLR-2 or the shared TLR adapter molecule MyD88 have been shown to result in greatly increased bacterial burdens in mice. However, although in vitro studies have shown that the act...

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Detalhes bibliográficos
Main Authors: Behera, Aruna K., Hildebrand, Ethan, Bronson, Roderick T., Perides, George, Uematsu, Satoshi, Akira, Shizuo, Hu, Linden T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1418660/
https://ncbi.nlm.nih.gov/pubmed/16495516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.3.1462-1470.2006
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