MyD88 Deficiency Enhances Acquisition and Transmission of Borrelia burgdorferi by Ixodes scapularis Ticks

Borrelia burgdorferi strains exhibit various degrees of infectivity and pathogenicity in mammals, which may be due to their relative ability to evade initial host immunity. Innate immune cells recognize B. burgdorferi by Toll-like receptors (TLRs) that use the intracellular molecule MyD88 to mediate...

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Detalhes bibliográficos
Main Authors: Bockenstedt, Linda K., Liu, Nengyin, Schwartz, Ira, Fish, Durland
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1418887/
https://ncbi.nlm.nih.gov/pubmed/16552045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.4.2154-2160.2006
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