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MyD88 Deficiency Enhances Acquisition and Transmission of Borrelia burgdorferi by Ixodes scapularis Ticks

Borrelia burgdorferi strains exhibit various degrees of infectivity and pathogenicity in mammals, which may be due to their relative ability to evade initial host immunity. Innate immune cells recognize B. burgdorferi by Toll-like receptors (TLRs) that use the intracellular molecule MyD88 to mediate...

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Bibliografiska uppgifter
Huvudupphovsmän: Bockenstedt, Linda K., Liu, Nengyin, Schwartz, Ira, Fish, Durland
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2006
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1418887/
https://ncbi.nlm.nih.gov/pubmed/16552045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.4.2154-2160.2006
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