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MyD88 Deficiency Enhances Acquisition and Transmission of Borrelia burgdorferi by Ixodes scapularis Ticks

Borrelia burgdorferi strains exhibit various degrees of infectivity and pathogenicity in mammals, which may be due to their relative ability to evade initial host immunity. Innate immune cells recognize B. burgdorferi by Toll-like receptors (TLRs) that use the intracellular molecule MyD88 to mediate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bockenstedt, Linda K., Liu, Nengyin, Schwartz, Ira, Fish, Durland
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1418887/
https://ncbi.nlm.nih.gov/pubmed/16552045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.4.2154-2160.2006
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