Dual Role of MyD88 in Rapid Clearance of Relapsing Fever Borrelia spp.

Relapsing fever Borrelia spp. undergo antigenic variation, achieve high levels in blood, and require rapid production of immunoglobulin M (IgM) for clearance. MyD88-deficient mice display defective clearance of many pathogens; however, the IgM response to persistent infection is essentially normal....

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Autori principali: Bolz, Devin D., Sundsbak, Rhianna S., Ma, Ying, Akira, Shizuo, Weis, John H., Schwan, Tom G., Weis, Janis J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
Soggetti:
Host Response and Inflammation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698049/
https://ncbi.nlm.nih.gov/pubmed/17030581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01160-06
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