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Distinct Roles for MyD88 and Toll-Like Receptors 2, 5, and 9 in Phagocytosis of Borrelia burgdorferi and Cytokine Induction

The contribution of Toll-like receptors (TLRs) to phagocytosis of Borrelia burgdorferi has not been extensively studied. We show that bone marrow-derived macrophages (BMDM) from MyD88(−/−) mice or Raw cells transfected with a dominant-negative MyD88 were unable to efficiently internalize B. burgdorf...

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Detalhes bibliográficos
Main Authors: Shin, Ok S., Isberg, Ralph R., Akira, Shizuo, Uematsu, Satoshi, Behera, Aruna K., Hu, Linden T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423091/
https://ncbi.nlm.nih.gov/pubmed/18378636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01600-07
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