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The Mechanisms of Catalysis by Metallo β-Lactamases

Class B β-lactamases or metallo-β-lactamases (MBLs) require zinc ions to catalyse the hydrolysis of β-lactam antibiotics such as penicillins, cephalosporins, carbapenems, and cephamycins. There are no clinically useful inhibitors against MBLs which are responsible for the resistance of some bacteria...

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Main Authors: Page, Michael I., Badarau, Adriana
格式: Artigo
語言:Inglês
出版: Hindawi Publishing Corporation 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2422870/
https://ncbi.nlm.nih.gov/pubmed/18551183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2008/576297
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