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The Continuing Challenge of Metallo-β-Lactamase Inhibition: Mechanism Matters
Metallo-β-lactamases (MBLs) are a significant clinical problem because they hydrolyze and inactivate nearly all β-lactam containing antibiotics. These “lifesaving drugs” constitute >50% of the available contemporary antibiotic arsenal. Despite the global spread of MBLs, MBL inhibitors have not ye...
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| Publicado no: | Trends Pharmacol Sci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6005755/ https://ncbi.nlm.nih.gov/pubmed/29680579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2018.03.007 |
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