Identification of a thiamin-dependent synthase in Escherichia coli required for the formation of the 1-deoxy-d-xylulose 5-phosphate precursor to isoprenoids, thiamin, and pyridoxol

In Escherichia coli, 1-deoxy-d-xylulose (or its 5-phosphate, DXP) is the biosynthetic precursor to isopentenyl diphosphate [Broers, S. T. J. (1994) Dissertation (Eidgenössische Technische Hochschule, Zürich)], thiamin, and pyridoxol [Himmeldirk, K., Kennedy, I. A., Hill, R. E., Sayer, B. G. & Sp...

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Detalhes bibliográficos
Main Authors: Sprenger, Georg A., Schörken, Ulrich, Wiegert, Thomas, Grolle, Sigrid, de Graaf, Albert A., Taylor, Sean V., Begley, Tadhg P., Bringer-Meyer, Stephanie, Sahm, Hermann
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC24228/
https://ncbi.nlm.nih.gov/pubmed/9371765
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