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Thiamin Diphosphate Activation in 1-Deoxy-D-xylulose 5-Phosphate Synthase: Insights into the Mechanism and Underlying Intermolecular Interactions
1-Deoxy-D-xylulose 5-phosphate synthase (DXS) is a thiamin diphosphate (TDP) dependent enzyme that marks the beginning of the methylerythritol 4-phosphate isoprenoid biosynthesis pathway. The mechanism of action for DXS is still poorly understood and begins with the formation of a thiazolium ylide....
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| Publicado no: | J Phys Chem B |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5379999/ https://ncbi.nlm.nih.gov/pubmed/27537621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.6b07248 |
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