Identification of a GH110 Subfamily of α1,3-Galactosidases: NOVEL ENZYMES FOR REMOVAL OF THE α3GAL XENOTRANSPLANTATION ANTIGEN

In search of α-galactosidases with improved kinetic properties for removal of the immunodominant α1,3-linked galactose residues of blood group B antigens, we recently identified a novel prokaryotic family of α-galactosidases (CAZy GH110) with highly restricted substrate specificity and neutral pH op...

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Detalhes bibliográficos
Main Authors: Liu, Qiyong P., Yuan, Huaiping, Bennett, Eric P., Levery, Steven B., Nudelman, Edward, Spence, Jean, Pietz, Greg, Saunders, Kristen, White, Thayer, Olsson, Martin L., Henrissat, Bernard, Sulzenbacher, Gerlind, Clausen, Henrik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2417185/
https://ncbi.nlm.nih.gov/pubmed/18227066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709020200
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