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Effects of Mutagenic and Chain-Terminating Nucleotide Analogs on Enzymes Isolated from Hepatitis C Virus Strains of Various Genotypes

The development of effective therapies for hepatitis C virus (HCV) must take into account genetic variation among HCV strains. Response rates to interferon-based treatments, including the current preferred treatment of pegylated alpha interferon administered with ribavirin, are genotype specific. Of...

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Detalhes bibliográficos
Main Authors: Heck, Julie A., Lam, Angela M. I., Narayanan, Nirupama, Frick, David N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2415805/
https://ncbi.nlm.nih.gov/pubmed/18391043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01496-07
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